General description

Toyopearl GigaCap Q-650 resin is a high capacity, high resolution anion exchange resin* optimized for the capture and purification of both small and large proteins, including oligonucleotides and monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of anionic binding sites for increased resin capacity. Toyopearl GigaCap Q-650M resin exhibits typical dynamic binding capacities in the vicinity of 175 mg/mL for BSA and 49 mg/mL for thyroglobulin, whereas, Toyopearl GigaCap Q-650S has dynamic binding capacities approaching 190 g/L for bovine serum albumin.Toyopearl GigaCap Q-650 resin maintains high capacity at increased linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The high capacity, combined with the 35 µm mean particle size, makes Toyopearl GigaCap Q-650S ideal for high resolution applications.In addition to the high DBC and good pressure flow characteristics, Toyopearl GigaCap Q-650 resin displays excellent binding and elution kinetics, which results in a more concentrated protein fraction collected during the elution step.*specifically designed for packed bed use

Legal Information

Toyopearl GigaCap is a registered trademark of Tosoh Corporation

Toyopearl is a registered trademark of Tosoh Corporation

Physical form

72% (v/v) slurry in 20% (v/v) ethanol

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Specifications

Clean in place with 0.5 M NaOH or 0.1 M HCl.